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4-Acetoxy-N-methyl-N-isopropyltryptamine (abbreviated 4-AcO-MiPT and also known as mipracetin) is a synthetic psychedelic tryptamine. It is the acetylated form of 4-HO-MiPT (also known as miprocin) and is a higher homolog of 4-AcO-DMT, 4-AcO-MET and 4-AcO-DET. These substances are commonly hypothesized to act primarily as prodrugs for their respective hydroxylated counterparts (e.g. 4-HO-DMT, 4-HO-MET and 4-HO-DET).

4-AcO-MiPT, or 4-Acetoxy-N-isopropyl-N-methyltryptamine, is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-AcO-MiPT is substituted at R4 of its indole heterocycle with an acetoxy (AcO) functional group CH3COO−. It also contains isopropyl and methyl chains bound to the terminal amine RN of its tryptamine backbone (MiPT).

4-AcO-MiPT is the N-substituted methisopropyl homologue of 4-HO-DMT (psilocin). 4-AcO-MiPT is the acetate ester analog of MiPT and the N-substituted methisopropyl analog of 4-AcO-DMT.

Like with most psychedelic tryptamines, 4-AcO-MiPT is thought to act principally as a 5-HT2A partial agonist. The psychedelic effects are believed to come from 4-AcO-MiPT's binding efficacy at the 5-HT2A receptors.

In terms of its effects on the physical energy levels of the tripper, 4-AcO-MiPT is considered by most to be relaxing, stoning and mildly sedating. This sense of sedation is often accompanied by uncontrollable yawning.

The "body high" of 4-AcO-MiPT can be described as a pleasurable, warm, soft and all-encompassing tingling sensation. This maintains a consistent presence that steadily rises with the onset and hits its limit once the peak has been reached.

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4-AcO-MiPT stock last updated at: December 2024

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